Coyote's Natural Medicine Bone and Bruise Cream is used for bruising, muscle aches, sprains, painful joints, localized arthritis pain, tendinitis, sore tendons, sore ligaments, & sore muscles. Use: Apply topically as needed. Ingredients: Organic Comfrey, Arnica & peppermint in a glycerin base. Note: Do Not apply on open wounds, instead use the Healing Cream that we offer.